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Published TCIMAIL newest issue No.198
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CAS RN: 73151-29-8 | Product Number: F1008
Fenticonazole Nitrate
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Purity: >97.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 200MG |
57,00 €
|
3 | 14 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | F1008 |
| Purity / Analysis Method | >97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__4H__2__0Cl__2N__2OS·HNO__3 = 518.41 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 73151-29-8 |
| Related CAS RN | 72479-26-6 |
| PubChem Substance ID | 253661427 |
| Merck Index (14) | 4005 |
| MDL Number | MFCD00941391 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Melting point | 133.0 to 137.0 °C |
Properties (reference)
| Melting Point | 135 °C |
GHS
Related Laws:
| EC Number | 277-302-6 |
| RTECS# | NI4780000 |
Transport Information:
| HS Number | 2933299090 |
Application
Fenticonazole Nitrate: An Imidazole Antifungal Agent
Fenticonazole nitrate is an imidazole antifungal agent with a broad spectrum of antimycotic activity against dermatophytes and yeasts. The main mechanism of action of fenticonazole is based on the inhibition of the synthesis of aspartic protease, a virulence enzyme of fungus. Fenticonazole has activity against Gram-positive bacteria, but no activity against Gram-negative bacteria. Fenticonazole used as a racemic mixture in therapy. (The product is for research purpose only.)
References
- Physicochemical, structural and analytical studies on fenticonazole, a new drug with antimycotic properties
- Comparison of the in vitro activities of fenticonazole, other imidazoles, metronidazole, and tetracycline against organisms associated with bacterial vaginosis and skin infections
- In vitro activity of sertaconazole, fluconazole, ketoconazole, fenticonazole, clotrimazole and itraconazole against pathogenic vaginal yeast isolates
- Topical fenticonazole in dermatology and gynaecology: current role in therapy (a review)
- HPLC analysis of imidazole antimycotic drugs in pharmaceutical formulations
- Chiral discrimination by HPLC and CE and antifungal activity of racemic fenticonazole and its enantiomers
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