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Published TCIMAIL newest issue No.198
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CAS RN: 25451-15-4 | Product Number: F1039
Felbamate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 2-Phenyl-1,3-propanediol Dicarbamate
- 2-Phenylpropane-1,3-diyl Dicarbamate
- 3-(Carbamoyloxy)-2-phenylpropyl Carbamate
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 100MG |
€147.00
|
1 | ≥60 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | F1039 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__1H__1__4N__2O__4 = 238.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 25451-15-4 |
| Reaxys Registry Number | 3345236 |
| MDL Number | MFCD00865296 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Volumetric Analysis) | min. 98.0 % |
| Melting point | 151.0 to 155.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 153 °C |
GHS
| Pictogram |
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| Signal Word | Warning |
| Hazard Statements | H373 : May cause damage to organs through prolonged or repeated exposure. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P314 : Get medical advice/ attention if you feel unwell. |
Related Laws:
| EC Number | 247-001-4 |
| RTECS# | TZ1070000 |
Transport Information:
| HS Number | 2924297099 |
Application
Felbamate: An inhibitor of NMDA Receptors and a Modulator of GABBA Receptors
Felbamate is an anticonvulsant agent. Although the mechanism of action is not fully understood, it has been reported that felbamate inhibits N-methyl-D-aspartate (NMDA) receptors and positively modulates γ-aminobutyric acidA (GABAA) receptors. (The product is for research purpose only.)
References
- Mechanism of action of the anticonvulsant felbamate: opposing effects on N-methyl-D-aspartate and γ-aminobutyric acidA receptors
- Felbamate displays in vitro antiepileptic effects as a broad spectrum excitatory amino acid receptor antagonist
- Felbamate: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in epilepsy
- Mechanisms of action of antiepileptic drugs (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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