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CAS RN: 13609-67-1 | Product Number: H1506
Hydrocortisone 17-Butyrate
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Purity: >98.0%(HPLC)
Synonyms:
- 11β,17,21-Trihydroxypregn-4-ene-3,20-dione 17-Butyrate
- Cortisol 17-Butyrate
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 200MG |
24,00 €
|
2 | ≥40 | |
| 1G |
79,00 €
|
2 | 9 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | H1506 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__3__6O__6 = 432.56 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 13609-67-1 |
| Reaxys Registry Number | 3634702 |
| PubChem Substance ID | 253660488 |
| Merck Index (14) | 4787 |
| MDL Number | MFCD00083364 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 207.0 to 212.0 °C |
| Specific rotation [a]20/D | +48.0 to +52.0 deg(C=0.1,CHCl3)(calcd.on dried substance) |
| Drying loss | max. 1.0 % |
Properties (reference)
| Melting Point | 212 °C |
| Specific Rotation | 50° (C=0.1,CHCl3) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 237-093-4 |
| RTECS# | GM9002000 |
Transport Information:
| HS Number | 2937210000 |
Application
Hydrocortisone 17-Butyrate: A Non-Fluorinated Synthetic Corticosteroid with Anti-Inflammatory
Hydrocortisone 17-butyrate is a non-fluorinated synthetic corticosteroid with anti-inflammatory, antieczematous, anti-allergic and anti-pruritic properties for used in psoriasis, eczema and other inflammatory dermatoses. The effective formulation on dermal absorption of hydrocortisone 17-butyrate has been studied. (The product is for research purpose only.)
References
- Hydrocortisone 17-butyrate: a new topical corticosteroid. Preliminary report (a review)
- The use of N,N-diethyl-m-toluamide to enhance dermal and transdermal delivery of drugs
- Inclusion complexation of hydrocortisone butyrate with cyclodextrins and dimethyl-β-cyclodextrin in aqueous solution and in solid state
- Influence of propylene glycol as cosolvent on mechanisms of drug transport from hydrogels
- The comparative effects of tacrolimus and hydrocortisone in adult atopic dermatitis: an immunohistochemical study
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