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Published TCIMAIL newest issue No.201
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CAS RN: 19210-12-9 | Product Number: H1849
Harpagoside
×
Purity: >95.0%(HPLC)
Synonyms:
- (1S,4aS,5R,7S,7aS)-1,4a,5,6,7,7a-Hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl β-D-Glucopyranoside
- (1S,4aR,5R,7S,7aR)-1-(β-D-Glucopyranosyloxy)-4a,5-dihydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-7-yl (2E)-3-Phenylacrylate
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 100MG |
173,00 €
|
Contact Us | 13 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | H1849 |
Purity / Analysis Method 
|
>95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__4H__3__0O__1__1 = 494.49 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 19210-12-9 |
| Reaxys Registry Number | 5192912 |
| MDL Number | MFCD00017415 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Specific rotation | -43.0 to -47.0 deg(C=1, methanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 132 °C |
GHS
Related Laws:
| EC Number | 242-881-6 |
| RTECS# | LZ5900200 |
Transport Information:
| HS Number | 2938909090 |
Application
Harpagoside: An Iridoid Glycoside with Remarkable Biological Properties
Harpagoside is an iridoid glycoside that was first isolated from Harpagophytum procumbens which is used as an anti-inflammatory traditional medicinal plant.1,2) It has been reported that harpagoside suppresses lipopolysaccharide-induced iNOS and COX-2 expression through inhibition of NF-κB activation.3,4) (The product is for research purpose only.)
References
- 1) Chapter 9 - Harpagophytum procumbens
- 2) Harpagoside: from Kalahari Desert to pharmacy shelf (a review)
- 3) Harpagoside suppresses lipopolysaccharide-induced iNOS and COX-2 expression through inhibition of NF-κB activation
- 4) Downregulation of iNOS expression in rat mesangial cells by special extracts of Harpagophytum procumbens derives from harpagoside-dependent and independent effects
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