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Published TCIMAIL newest issue No.201
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CAS RN: 75695-93-1 | Product Number: I0876
Isradipine
Purity: >98.0%(HPLC)
Synonyms:
- Isopropyl Methyl 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
- 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Isopropyl Methyl Ester
- Isopropyl Methyl 4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
- 4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Isopropyl Methyl Ester
Product Documents:
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | I0876 |
Purity / Analysis Method
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__1N__3O__5 = 371.39 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
Packaging and Container
|
25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 75695-93-1 |
| Reaxys Registry Number | 6576633 |
| PubChem Substance ID | 253659791 |
| Merck Index (14) | 5240 |
| MDL Number | MFCD00153820 |
Specifications
| Appearance | White to Light orange to Pale yellow green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 10.70 to 11.60 % |
| Melting point | 167.0 to 171.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 169 °C |
GHS
| Hazard Statements | H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
Related Laws:
Transport Information:
| HS Number | 2934999090 |
Application
Calcium Antagonist Isradipine
References
- Calcium antagonists isradipine and nimodipine suppress cocaine and morphine intravenous self-administration in drug-naive mice
- Ca2+ channel sensitivity towards the blocker isradipine is affected by alternative splicing of the human α1C subunit gene
- Effect of chronic dihydropyridine (isradipine) on the large arterial walls of spontaneously hypertensive rats
- Isradipine
- Isradipine - another calcium-channel blocker for the treatment of hypertension and angina
- L. M. Lopez, T. M. Santiago, Ann. Pharmacother. 1992, 26, 789.
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