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Published TCIMAIL newest issue No.201
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CAS RN: 130495-35-1 | Product Number: K0066
SKF-96365
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Purity: >98%(HPLC)
Synonyms:
- 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]-1H-imidazole Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 50MG |
€307.00
|
Contact Us | 37 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | K0066 |
Purity / Analysis Method 
|
>98%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__2__6N__2O__3·HCl = 402.92 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| CAS RN | 130495-35-1 |
| Reaxys Registry Number | 7402134 |
| PubChem Substance ID | 468592133 |
| MDL Number | MFCD00236407 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
Properties (reference)
| Melting Point | 119 °C |
GHS
Related Laws:
| RTECS# | NI6823500 |
Transport Information:
| HS Number | 2933299090 |
Application
SKF-96365: An Inhibitor of Receptor-Mediated Calcium Entry, and a TRPC Channel Antagonist
SKF-96365 is first reported as an inhibitor of receptor-mediated calcium entry.1) But recently, SKF-96365 is also used as an antagonist (blocker) of transient receptor potential canonical type (TRPC) channels which represent important molecules involved in hormonal signal transduction.2,3)
References
- 1) SK&F 96365, a novel inhibitor of receptor-mediated calcium entry
- 2) The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channels
- 3) Pharmacological modulation of diacylglycerol-sensitive TRPC3/6/7 channels (a review)
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