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Published TCIMAIL newest issue No.201
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CAS RN: 74381-53-6 | Product Number: L0249
Leuprorelin Acetate
Purity: >97.0%(HPLC)
Synonyms:
- Leuprolide Acetate
Product Documents:
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| Product Number | L0249 |
Purity / Analysis Method
|
>97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__5__9H__8__4N__1__6O__1__2·C__2H__4O__2 = 1,269.47 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
Packaging and Container
|
25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 74381-53-6 |
Related CAS RN
|
53714-56-0 |
| Reaxys Registry Number | 5570787 |
| PubChem Substance ID | 253659667 |
| Merck Index (14) | 5457 |
| MDL Number | MFCD00167544 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Specific rotation [a]20/D | -31.0 to -35.0 deg(C=1,AcOH(1%)) |
| NMR | confirm to structure |
Properties (reference)
| Specific Rotation | -34° (C=1,1%AcOH) |
GHS
Related Laws:
| RTECS# | OH6390000 |
Transport Information:
| HS Number | 2937190000 |
Application
Studies on the Pharmacological Activity of Leuprorelin Acetate as a Gonadotropin-releasing Hormone (GnRH) Antagonist
References
- GnRH antagonist in assisted reproduction: a Cochrane review
- Leuprolide acetate: A drug of diverse clinical applications
Application
Studies of Leuprorelin Acetate Drug Delivery System (DDS)
References
- A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic)acid
- One- and three-month release injectable microspheres of the LH-RH superagonist leuprorelin acetate
- Preparation of three-month depot injectable microspheres of leuprorelin acetate using biodegradable polymers
- H. Okada, Y. Doken, Y. Ogawa, H. Toguchi, Pharm. Res. 1994, 11, 1143.
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