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Published TCIMAIL newest issue No.201
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CAS RN: 63177-57-1 | Product Number: M2520
Methyl 2,5-Dihydroxycinnamate
Purity: >96.0%(HPLC)
Synonyms:
- 2,5-Dihydroxycinnamic Acid Methyl Ester
- Erbstatin Analog
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 10MG |
32,00 €
|
2 | Contact Us | |
| 100MG |
216,00 €
|
Contact Us | Contact Us |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | M2520 |
Purity / Analysis Method
|
>96.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__0O__4 = 194.19 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 63177-57-1 |
| Reaxys Registry Number | 8140004 |
| PubChem Substance ID | 354334085 |
| MDL Number | MFCD00132932 |
Specifications
| Appearance | White to Yellow powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Melting point | 180.0 to 184.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 182 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| HS Number | 2918290090 |
Application
A Stable Analog of Erbstatin, a Tyrosine Kinase Inhibitor
This reagent is a stable analog of erbstatin which is a naturally occurring tyrosine kinase inhibitor. This reagent is also used as a tyrosine kinase inhibitor; especially in an epidermal growth factor receptor (EGFR) associated tyrosine kinase inhibitor.
References
- Inhibition of epidermal growth factor-induced DNA synthesis by tyrosine kinase inhibitors
- The tyrosine kinase inhibitors methyl 2,5-dihydroxycinnamate and genistein reduce thrombin-evoked tyrosine phosphorylation and calcium entry in human platelets
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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