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CAS RN: 19457-55-7 | Product Number: M3121
6-Methyleneandrost-4-ene-3,17-dione
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Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 1G |
€21.00
|
Contact Us | 1 | |
| 5G |
€67.00
|
1 | 12 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | M3121 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__6O__2 = 298.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 19457-55-7 |
| Reaxys Registry Number | 4514172 |
| PubChem Substance ID | 354335792 |
| MDL Number | MFCD09038727 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +390 to +430 deg(C=1, CHCL3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 164 °C(dec.) |
| Specific Rotation | 411° (C=1,CHCl3) |
| Maximum Absorption Wavelength | 259 nm (EtOH) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
Transport Information:
| HS Number | 2914290090 |
Application
A Synthetic Intermediate of Exemestane
This product is a synthetic intermediate of exemestane (FCE 24304) [E0941] which is a potent and selective aromatase inhibitor.
References
- 6-Methylenandrosta-1,4-diene-3,17-dione (FCE 24304): a new irreversible aromatase inhibitor
- Synthesis and aromatase inhibition by potential metabolites of exemestane (6-methylenandrosta-1,4-diene-3,17-dione)
- 1,2-Dehydrogenation of steroidal 6-methylene derivatives. Synthesis of exemestane
- Development and validation of a stability indicating LC method for the assay and related substances determination of Exemestane, an aromatase inhibitor
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