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CAS RN: 51481-60-8 | Product Number: N1254
Naloxone Hydrochloride Dihydrate
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Purity: >95.0%(HPLC)
Synonyms:
- 17-Allyl-3,14-dihydroxy-5α-4,5-epoxymorphinan-6-one Hydrochloride Dihydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 10MG |
€ 100,00
|
Contact Us | 1 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | N1254 |
Purity / Analysis Method 
|
>95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__1NO__4·HCl·2H__2O = 399.87 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic,Heat Sensitive |
| CAS RN | 51481-60-8 |
| Reaxys Registry Number | 6260807 |
| MDL Number | MFCD00150901 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Water | 8.5 to 10.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 182 °C |
| Solubility (soluble in) | Methanol |
| Solubility (insoluble in) | Diethyl ether |
GHS
Related Laws:
Transport Information:
| HS Number | 2939190000 |
Application
Naloxone Hydrochloride: A Competitive Peripheral μ-Opioid Antagonist
Naloxone hydrochloride, a competitive peripheral μ-opioid antagonist, is a synthetic congener of opioid analgesics with little or no μ-opioid agonist properties. It is used clinically for the treatment of opioid dependence and opioid-induced respiratory depression, sedation, and hypotension. (The product is for research purpose only.)
References
- Drugs Five Years Later: Naloxone (a review)
- New and experimental therapeutic roles for naloxone and related opioid antagonists (a review)
- Buprenorphine/naloxone. A review of its use in the treatment of opioid dependence
- Naloxone hydrochloride (A review of the chemistry, synthesis, metabolism, and methods of analysis)
- Development and validation of a HPLC method for the determination of buprenorphine hydrochloride, naloxone hydrochloride, and noroxymorphone in a tablet formulation
Product Documents (Note: Some products will not have analytical charts available.)
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