Published TCIMAIL newest issue No.199
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 751-03-1 | Product Number: O0506
Obacunone
×
![]()
×
Purity: >98.0%(HPLC)
Synonyms:
- Obacunoic Acid ε-Lactone
- Obacunoic Acid 3,4-Lactone
- (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(Furan-3-yl)-4b,7,7,11a,13a-pentamethyl-1,6a,7,11a,11b,12,13,13a-octahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromene-3,5,9(3aH,4bH,6H)-trione
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 100MG |
€ 345,00
|
Contact Us | 22 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | O0506 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__6H__3__0O__7 = 454.52 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 751-03-1 |
| Related CAS RN
|
6483-15-4 |
| Reaxys Registry Number | 68347 |
| MDL Number | MFCD00075888 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 227.0 to 231.0 °C |
| Specific rotation | -49.0 to -53.0 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 229 °C |
GHS
Related Laws:
| RTECS# | RR1104200 |
Transport Information:
| HS Number | 2932209090 |
Application
Obacunone: A Type of Limonoid with Various Pharmacological Activities Such As Anticancer and Anti-Inflammatory
Limonoids are a class of oxygenated terpenoids found primarily in citrus fruits. Obacunone is a type of limonoid with various pharmacological activities such as anticancer, antioxidant, anti-inflammatory, antidiabetic, neuroprotective, antibiosis, and antiviral. Among them, the anticancer effect is the most prominent. (The product is for research purpose only.)
References
- The pharmacological and pharmacokinetic properties of obacunone from citrus fruits: A comprehensive narrative review
- Obacunone and obacunone glucoside inhibit human colon cancer (SW480) cells by the induction of apoptosis
- Obacunone causes sustained expression of MKP-1 thus inactivating p38 MAPK to suppress pro-inflammatory mediators through intracellular MIF
- Simultaneous determination of limonin, dictamnine, obacunone and fraxinellone in rat plasma by a validated UHPLC-MS/MS and its application to a pharmacokinetic study after oral administration of Cortex Dictamni extract
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.