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CAS RN: 23288-49-5 | Product Number: P2002
Probucol
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Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 5G |
€39.00
|
1 | 4 | |
| 25G |
€124.00
|
1 | ≥60 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | P2002 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__3__1H__4__8O__2S__2 = 516.84 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive |
| CAS RN | 23288-49-5 |
| Reaxys Registry Number | 2026253 |
| PubChem Substance ID | 160871250 |
| Merck Index (14) | 7755 |
| MDL Number | MFCD00079281 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 125.0 to 128.0 °C |
Properties (reference)
| Melting Point | 128 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Methanol, Acetone, Tetrahydrofuran |
GHS
Related Laws:
| EC Number | 245-560-9 |
| RTECS# | AL3705000 |
Transport Information:
| HS Number | 2930909599 |
Application
Studies of the Effects of Probucol on Low Density Lipoproteins (LDL)
References
- Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit
- Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemia rabbit, an animal model for familial hypercholesterolemia
- Probucol inhibits oxidative modification of low density lipoprotein
- Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation
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