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CAS RN: 58-33-3 | Product Number: P2029
Promethazine Hydrochloride
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 10-[2-(Dimethylamino)propyl]phenothiazine Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 25G |
€53.00
|
8 | 14 | |
| 100G |
€169.00
|
2 | 10 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | P2029 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__2__0N__2S·HCl = 320.88 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| CAS RN | 58-33-3 |
| Related CAS RN
|
60-87-7 |
| Reaxys Registry Number | 4166397 |
| PubChem Substance ID | 160871508 |
| Merck Index (14) | 7786 |
| MDL Number | MFCD00012652 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 226 °C |
| Maximum Absorption Wavelength | 297 nm (H__2O) |
| Solubility (insoluble in) | Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H411 : Toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P391 : Collect spillage. P337 + P313 : If eye irritation persists: Get medical advice/ attention. |
Related Laws:
| EC Number | 200-375-2 |
| RTECS# | SO8225000 |
Transport Information:
| UN Number | UN3077 |
| Class | 9 |
| Packing Group | III |
| HS Number | 2934309090 |
Application
Efflux pump research / Biofilm research
References
- Antifungal activity of promethazine and chlorpromazine against planktonic cells and biofilms of Cryptococcus neoformans/Cryptococcus gattii complex species
- The Role of Efflux Pumps and Environmental pH in Bacterial Multidrug Resistance
- Synergistic Effects of Efflux Pump Modulators on the Azole Antifungal Susceptibility of Microsporum canis
- In vitro effects of promethazine on cell morphology and structure and mitochondrial activity of azole-resistant Candida tropicalis
Application
Formulation and its Related Studies of Promethazine Hydrochloride
References
- Formulation of sustained-release promethazine hydrochloride tablets using hydroxypropyl methyl cellulose matrixes
- Adsorption of promethazine hydrochloride with KSF montmorillonite
- Release of cationic drugs from loaded clay minerals
- I. Fejer, M. Kata, I. Eros, O. Berkesi, I. Dekany, Colloid. Polym. Sci. 2001, 279, 1177.
- Colorimetric determination of captopril in dosage forms
- S. M. El-Ashry, F. A. Ibrahim, Anal. Lett. 1992, 25, 1657.
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