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Published TCIMAIL newest issue No.198
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CAS RN: 121808-62-6 | Product Number: P2147
Pidotimod
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (R)-3-[[(S)-5-Oxo-2-pyrrolidinyl]carbonyl]-1,3-thiazolidine-4-carboxylic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 5G |
€163.00
|
1 | 12 |
| 25G |
€574.00
|
Contact Us | 3 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | P2147 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__9H__1__2N__2O__4S = 244.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 121808-62-6 |
| Reaxys Registry Number | 6636310 |
| PubChem Substance ID | 253661767 |
| Merck Index (14) | 7419 |
| MDL Number | MFCD00867583 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -135 to -145 deg(C=2, 5mol/L HCl) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 187 °C(dec.) |
| Specific Rotation | -136° (C=2,5mol/L HCl) |
| Solubility in water | Soluble |
| Solubility (soluble in) | Dimethylformamide |
| Solubility (slightly sol. in) | Methanol |
GHS
Related Laws:
| RTECS# | XJ5426675 |
Transport Information:
| HS Number | 2934999090 |
Application
Pidotimod: A Synthetic Dipeptide with Immunomodulating Activity
Pidotimod is a synthetic dipeptide molecular with immunomodulating effect.
References
- Synthesis and preliminary pharmacological evaluation of Pidotimod, its enantiomer, diastereomers and carboxamido derivatives
- A. Magni, G. Signorelli, G. Bocchiola, Arzneim.-Forsch. 1994, 44, 1402.
- Synergistic immunostimulating activity of pidotimod and red ginseng acidic polysaccharide against cyclophosphamide-induced immunosuppression
- Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level
- Pidotimod: a reappraisal (a review)
- Pidotimod: the past and the present (a review)
PubMed Literature
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