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CAS RN: 88069-49-2 | Product Number: P2634
Pilsicainide Hydrochloride
Purity: >98.0%(HPLC)
Synonyms:
- N-(2,6-Dimethylphenyl)tetrahydro-1H-pyrrolizine-7a(5H)-acetamide Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 50MG |
€46.00
|
Contact Us | 4 | |
| 250MG |
€154.00
|
Contact Us | 19 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | P2634 |
Purity / Analysis Method
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__2__4N__2O·HCl = 308.85 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 88069-49-2 |
Related CAS RN
|
88069-67-4 |
| Reaxys Registry Number | 5667808 |
| PubChem Substance ID | 468592643 |
| Merck Index (14) | 7427 |
| MDL Number | MFCD00903769 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Argentometric Titration) | min. 97.0 % |
| Melting point | 211.0 to 215.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 213 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | UY7758200 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2933998090 |
Application
Pilsicainide Hydrochloride: A Relatively Pure Cardiac Sodium Channel Blocker
Pilsicainide hydrochloride, classified as a relatively pure cardiac sodium channel blocker, occasionally causes QT prolongation. It is a Vaughan Williams class Ic antiarrhythmic agent used for the treatment of supraventricular and ventricular arrhythmias. (The product is for research purpose only.)
References
- New antiarrhythmic agents. N-Aryl-8-pyrrolizidinealkanamides
- Pilsicainide for atrial fibrillation (a review)
- Effect of cimetidine and probenecid on pilsicainide renal clearance in humans
- ELISA for the quantification of pilsicainide
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