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Published TCIMAIL newest issue No.198
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CAS RN: 17673-25-5 | Product Number: P2732
Phorbol
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Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 5MG |
€89.00
|
1 | 3 |
| 25MG |
€287.00
|
Contact Us | 9 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | P2732 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__8O__6 = 364.44 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 17673-25-5 |
| Reaxys Registry Number | 2341335 |
| PubChem Substance ID | 468592695 |
| Merck Index (14) | 7332 |
| MDL Number | MFCD00065450 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 251 °C(dec.) |
| Specific Rotation | 93° (C=1,H2O) |
| Solubility in water | Soluble |
| Solubility (soluble in) | Ethanol, Acetone |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | GZ0600000 |
Transport Information:
| HS Number | 2914409090 |
Application
Phorbol: A Tetracyclic Diterpene for the Synthesis of Various its Diesters Known for their Tumor Promoting Activity
Phorbol is a tetracyclic diterpene originally isolated from croton oil.1,2) It is used as a starting compound for the synthesis of various phorbol diesters, which generally known for their tumor promoting activity and often employed in biomedical research to activate the signal transduction enzyme protein kinase C (PKC).3)
References
- 1) A rapid method for isolating phorbol from croton oil
- 2) Nineteen-step total synthesis of (+)-phorbol
- 3) Phorbol esters: Structure, biological activity, and toxicity in animals (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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