Published TCIMAIL newest issue No.199
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 950762-95-5 | Product Number: P3226
PCI-34051
×
![]()
×
New
Purity: >95.0%(HPLC)(qNMR)
Synonyms:
- N-Hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 10MG |
€150.00
|
Contact Us | 12 |
| 50MG |
€530.00
|
Contact Us | 12 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | P3226 |
Purity / Analysis Method 
|
>95.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__1__7H__1__6N__2O__3 = 296.33 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 950762-95-5 |
| Reaxys Registry Number | 11340810 |
| MDL Number | MFCD11114393 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| Melting point | 155.0 to 159.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 157 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2933998090 |
Application
PCI-34051: An HDAC8-Specific Inhibitor
Recent studies have shown that histone deacetylase 8 (HDAC8) regulates the expression and activity of genes involved in cancer initiation and progression.1) Therefore, HDAC8 is a promising target in cancer research. PCI-34051, an HDAC8-specific inhibitor, has been used in such research.2,3) (The product is for research use only.)
References
- 1) The clinical significance of histone deacetylase-8 in human breast cancer (a review)
- 2) A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas
- 3) An Unbiased Approach To Identify Endogenous Substrates of "Histone" Deacetylase 8
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.