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CAS RN: 17318-31-9 | Product Number: Q0105
SQ 22536
×
Purity: >97.0%(GC)
Synonyms:
- 9-(Tetrahydro-2-furanyl)-9H-purin-6-amine
- 9-(Tetrahydro-2-furyl)adenine
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 10MG |
€81.00
|
1 | 8 | |
| 50MG |
€258.00
|
1 | 5 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | Q0105 |
Purity / Analysis Method 
|
>97.0%(GC) |
| Molecular Formula / Molecular Weight | C__9H__1__1N__5O = 205.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
10MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 17318-31-9 |
| Reaxys Registry Number | 534250 |
| PubChem Substance ID | 468592772 |
| MDL Number | MFCD00210216 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 97.0 % |
| Melting point | 163.0 to 170.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 165 °C |
| Maximum Absorption Wavelength | 260 nm |
GHS
Related Laws:
Transport Information:
| HS Number | 2934999090 |
Application
SQ22536: An Adenylyl Cyclase Inhibitor
SQ22536 is an adenylyl cyclase inhibitor. Adenylyl cyclase (or adenylate cyclase) is an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) [A0157 (Na salt)] to 3’,5’-cyclic adenosine monophosphate (cAMP) [A2381][A2112 (Na salt)]. Therefore, adenylyl cyclase inhibitors, including SQ22536, have many applications in biochemical and physiological research.
References
- Inhibition of adenylate cyclase of catfish and rat hepatocyte membranes by 9-(tetrahydro-2-furyl)adenine (SQ22536)
- Effects of the adenylyl cyclase inhibitor SQ22536 on iloprost-induced vasorelaxation and cyclic AMP elevation in isolated guinea-pig aorta
- cAMP-dependent signaling as a core component of the mammalian circadian pacemaker
- A new site and mechanism of action for the widely used adenylate cyclase inhibitor SQ22,536
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