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CAS RN: 545380-34-5 | Product Number: Q0109
QNZ
×
Purity: >98.0%(HPLC)
Synonyms:
- EVP4593
- N4-(4-Phenoxyphenethyl)quinazoline-4,6-diamine
- N4-[2-(4-Phenoxyphenyl)ethyl]-4,6-quinazolinediamine
- 6-Amino-4-[2-(4-phenoxyphenyl)ethylamino]quinazoline
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 5MG |
55,00 €
|
Contact Us | 3 | |
| 25MG |
193,00 €
|
Contact Us | 2 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | Q0109 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__2__0N__4O = 356.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Heat Sensitive |
| CAS RN | 545380-34-5 |
| Reaxys Registry Number | 9350957 |
| PubChem Substance ID | 468592774 |
| MDL Number | MFCD06411436 |
Specifications
| Appearance | White to Light yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 182.0 to 186.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 184 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| HS Number | 2933599590 |
Application
Potent NF-κB activation inhibitor
References
- Discovery of quinazolines as a novel structural class of potent inhibitors of NF-κB activation
- Regorafenib induces extrinsic and intrinsic apoptosis through inhibition of ERK/NF-κB activation in hepatocellular carcinoma cells
- The Selection of NFκB Inhibitors to Block Inflammation and Induce Sensitisation to FasL-Induced Apoptosis in HNSCC Cell Lines Is Critical for Their Use as a Prospective Cancer Therapy
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