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Published TCIMAIL newest issue No.198
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CAS RN: 84-26-4 | Product Number: R0102
Rutaecarpine
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Purity: >98.0%(HPLC)(N)
Synonyms:
- 8,13-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 200MG |
€59.00
|
1 | ≥40 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | R0102 |
Purity / Analysis Method 
|
>98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__8H__1__3N__3O = 287.32 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 84-26-4 |
| Reaxys Registry Number | 34916 |
| PubChem Substance ID | 160871510 |
| Merck Index (14) | 8298 |
| MDL Number | MFCD00210551 |
Specifications
| Appearance | Light orange to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 262 °C |
GHS
Related Laws:
| RTECS# | NM3454000 |
Transport Information:
| HS Number | 2939799090 |
Application
Rutaecarpine: A Bioactive Indole Alkaloid Contained in Evodia rutaecarpa (Rutaceae)
Rutaecarpine is a bioactive indole alkaloid first isolated from Evodia rutaecarpa (Rutaceae) which is used as a traditional Chinese medicine for the treatment of cardiovascular diseases.1,2) Many studies indicate that rutaecarpine has biological effects such as inotropic, vasorelaxant, anti-platelet aggregation, and anti-inflammatory effects.2-4) In addition, rutaecarpine inhibits COX-1 and COX-2 activities.2,5) (The product is for research purpose only.)
References
- 1) Quality evaluation of Evodia rutaecarpa (Juss.) Benth by high performance liquid chromatography with photodiode-array detection
- 2) Progress in the studies on rutaecarpine (a review)
- 3) Pharmacological effects of rutaecarpine as a cardiovascular protective agent (a review)
- 4) Progress in Studies on Rutaecarpine. II.--Synthesis and Structure-Biological Activity Relationships
- 5) A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa
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