Maintenance notice in CEST time zone (1:00 - 3:30 AM May 17, 2026): Our website is scheduled for maintenance. The website will be available, but some functions may experience errors. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.201
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 155213-67-5 | Product Number: R0116
Ritonavir
×
Purity: >98.0%(HPLC)(N)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 200MG |
€47.00
|
1 | 2 | |
| 1G |
€152.00
|
6 | ≥40 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | R0116 |
Purity / Analysis Method 
|
>98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__3__7H__4__8N__6O__5S__2 = 720.95 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 155213-67-5 |
| Reaxys Registry Number | 7680098 |
| PubChem Substance ID | 253660208 |
| Merck Index (14) | 8238 |
| MDL Number | MFCD00927142 |
Specifications
| Appearance | White to Almost white powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 122.0 to 127.0 °C |
| Specific rotation [a]20/D | +7.0 to +10.0 deg(C=2,MeOH) |
Properties (reference)
| Melting Point | 125 °C |
| Specific Rotation | 8° (C=2,MeOH) |
| Solubility in water | Insoluble |
| Solubility (slightly sol. in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P261 : Avoid breathing dust. P273 : Avoid release to the environment. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. |
Related Laws:
| RTECS# | XA5310000 |
Transport Information:
| HS Number | 2934100090 |
Application
Ritonavir: a Booster of Other Protease Inhibitors
Ritonavir was originally developed as an inhibitor of HIV protease inhibitor (PI). Ritonavir is currently exclusively used as a pharmacokinetic enhancer (booster) of other protease inhibitors, due to ritonavir's potent inhibition of the cytochrome P 450 3A4 (CYP3A4), an enzyme that is responsible for metabolizing most HIV PIs.
References
- A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease
- A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection
- Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes
- Pharmacokinetic enhancers for HIV drugs
- M. W. Hull, J. S. G. Montaner, Curr. Opin. Invest. Drugs 2009, 10, 775.
- Ritonavir-boosted protease inhibitors in HIV therapy
PubMed Literature
Documents
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.