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Published TCIMAIL newest issue No.198
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CAS RN: 138844-81-2 | Product Number: S0877
Sodium Ibandronate
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Purity: >90.0%(T)
Synonyms:
- Ibandronic Acid Sodium Salt
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 1G |
€49.00
|
Contact Us | 21 |
| 5G |
€171.00
|
1 | 18 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | S0877 |
Purity / Analysis Method 
|
>90.0%(T) |
| Molecular Formula / Molecular Weight | C__9H__2__2NNaO__7P__2 = 341.21 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 138844-81-2 |
| Related CAS RN
|
114084-78-5 |
| Reaxys Registry Number | 14511791 |
| PubChem Substance ID | 160871235 |
| Merck Index (14) | 4873 |
| MDL Number | MFCD07197214 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(Neutralization titration) | min. 90.0 % |
| Drying loss | max. 10.0 % |
Properties (reference)
| Solubility in water | Soluble |
GHS
Related Laws:
| RTECS# | SZ8563300 |
Transport Information:
| HS Number | 2931498090 |
Application
Studies of the Inhibition of Bone Resorption
References
- Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras
- Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates
- J. E. Dunford, K. Thompson, F. P. Coxon, S. P. Luckman, F. M. Hahn, C. D. Poulter, F. H. Ebetino, M. J. Rogers, J. Pharmacol. Exp. Ther. 2001, 296, 235.
- Bisphosphonates act on rat bone resorption through the mediation of osteoblasts
- Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy
Application
Bone Resorption Inhibitors
References
- 1)Anti-bone resorption
- a)J. E. Dunford, K. Thompson, F. P. Coxon, S. P. Luckman, F. M. Hahn, C. D. Poulter, F. H. Ebetino, M. J. Rogers., J. Pharmacol. Exp. Ther. 2001, 296, 235.
- b)E. Hiroi-Furuya, T. Kameda, K. Hiura, H. Mano, K. Miyazawa, Y. Nakamaru, M. Watanabe-Mano, N. Okuda, J. Shimada, Y. Yamamoto, Y. Hakeda, M. Kumegawa, Calcif. Tissue Int. 1999, 64, 219.
- 2)In vitro anti-tumor effects and its in vivo role
PubMed Literature
Documents
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