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Published TCIMAIL newest issue No.201
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CAS RN: 152-47-6 | Product Number: S0917
Sulfalene
Purity: >98.0%(T)(HPLC)
Synonyms:
- 4-Amino-N-(3-methoxypyrazin-2-yl)benzenesulfonamide
- N-(3-Methoxypyrazin-2-yl)sulfanilamide
Product Documents:
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| Product Number | S0917 |
Purity / Analysis Method
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__1H__1__2N__4O__3S = 280.30 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 152-47-6 |
| Reaxys Registry Number | 622512 |
| PubChem Substance ID | 253660181 |
| Merck Index (14) | 8910 |
| MDL Number | MFCD00437754 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Volumetric Analysis) | min. 98.0 % |
| Melting point | 176.0 to 180.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 178 °C |
| Maximum Absorption Wavelength | 250 nm (NaOH aq.) |
| Solubility (slightly sol. in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H361 : Suspected of damaging fertility or the unborn child. H362 : May cause harm to breast-fed children. |
| Precautionary Statements | P263 : Avoid contact during pregnancy and while nursing. P260 : Do not breathe dust. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. |
Related Laws:
| EC Number | 205-804-7 |
| RTECS# | WP0175000 |
Transport Information:
| HS Number | 2933998090 |
Application
Sulfalene: An Anti-Malaria Sulfonamide Antibacterial Agent
Sulfalene is a sulfonamide antibacterial used as an anti-malaria agent.
References
- In vitro activities of and mechanisms of resistance to antifol antimalarial drugs
- Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern Nigeria
- Activities of Artemether-Lumefantrine and Amodiaquine-Sulfalene-Pyrimethamine against Sexual-Stage Parasites in Falciparum Malaria in Children
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