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CAS RN: 635-46-1 | Product Number: T0113
1,2,3,4-Tetrahydroquinoline
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Purity: >95.0%(GC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 25ML |
16,00 €
|
2 | 12 | |
| 100ML |
32,00 €
|
1 | 4 | |
| 500ML |
101,00 €
|
Contact Us | ≥100 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | T0113 |
Purity / Analysis Method 
|
>95.0%(GC) |
| Molecular Formula / Molecular Weight | C__9H__1__1N = 133.19 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Heat Sensitive |
| CAS RN | 635-46-1 |
| Reaxys Registry Number | 116149 |
| PubChem Substance ID | 87576121 |
| SDBS (AIST Spectral DB) | 3232 |
| MDL Number | MFCD00006693 |
Specifications
| Appearance | White or Colorless to Yellow to Orange powder to lump to clear liquid |
| Purity(GC) | min. 95.0 % |
| Freezing point | 11.0 to 20.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 13 °C |
| Boiling Point | 251 °C |
| Flash point | 113 °C |
| Specific Gravity (20/20) | 1.06 |
| Refractive Index | 1.59 |
| Solubility in water | Insoluble |
| Degree of solubility in water | < 1 g/l 20 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 211-237-6 |
Transport Information:
| HS Number | 2933499090 |
Application
Catalytic Formylation Using Tetrahydroisoquinoline
Experimental procedure:
4-Methoxyphenylboronic acid (20.0 mmol, 3.04 g) and glyoxylic acid monohydrate (21.0 mmol, 1.93 g) are placed in a flask. Acetonitrile (100 mL) is injected into the flask and then 1,2,3,4-ｔetrahydroquinoline (4.0 mmol, 0.5 mL) is added. The mixture is stirred at room temperature for 48 h exposed to air. After stirred for 48 h, the solvent is reduced in vacuo, and the residue is purified by column chromatography (SiO2, hexanes:EtOAc) to provide p-anisaldehyde (77% yield).
4-Methoxyphenylboronic acid (20.0 mmol, 3.04 g) and glyoxylic acid monohydrate (21.0 mmol, 1.93 g) are placed in a flask. Acetonitrile (100 mL) is injected into the flask and then 1,2,3,4-ｔetrahydroquinoline (4.0 mmol, 0.5 mL) is added. The mixture is stirred at room temperature for 48 h exposed to air. After stirred for 48 h, the solvent is reduced in vacuo, and the residue is purified by column chromatography (SiO2, hexanes:EtOAc) to provide p-anisaldehyde (77% yield).
References
- Synthesis of Aldehydes by Organocatalytic Formylation Reactions of Boronic Acids with Glyoxylic Acid
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