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CAS RN: 4602-84-0 | Product Number: T0608
Farnesol (mixture of isomers)
Purity:
Synonyms:
- 3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol (mixture of isomers)
Product Documents:
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| Product Number | T0608 |
| Molecular Formula / Molecular Weight | C__1__5H__2__6O = 222.37 |
| Physical State (20 deg.C) | Liquid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 4602-84-0 |
| Reaxys Registry Number | 1763926 |
| PubChem Substance ID | 87576502 |
| SDBS (AIST Spectral DB) | 5127 |
| Merck Index (14) | 3937 |
| MDL Number | MFCD00002918 |
Specifications
| Appearance | Colorless to Brown clear liquid |
| Purity(GC) | min. 95.0 %(total of isomer) |
Properties (reference)
| Boiling Point | 146 °C/3 mmHg |
| Flash point | 96 °C |
| Specific Gravity (20/20) | 0.89 |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Alcohol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H317 : May cause an allergic skin reaction. H410 : Very toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P273 : Avoid release to the environment. P261 : Avoid breathing mist or vapours. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves. P391 : Collect spillage. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 225-004-1 |
| RTECS# | JR4979000 |
Transport Information:
| UN Number | UN3082 |
| Class | 9 |
| Packing Group | III |
| HS Number | 2905220090 |
Application
Efflux pump inhibitor
Farnesol has been reported to act as an inhibitor of efflux pump in Mycobacterium smegmatis. According to the study comparing the inhibitory activity with those of other efflux pump inhibitors: chlorpromazine (C2481), reserpine (R0007), verapamil (V0118), and carbonyl cyanide m-chlorophenylhydrazone (CCCP, C2876), farnesol significantly enhanced the accumulation of ethidium bromide (E0370) and decreased the efflux of EtBr in the bacteria.1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Farnesol, a Potential Efflux Pump Inhibitor in Mycobacterium smegmatis
- The quorum-sensing molecules farnesol/homoserine lactone and dodecanol operate via distinct modes of action in Candida albicans
- Quorum sensing in Candida albicans: Probing farnesol’s mode of action with 40 natural and synthetic farnesol analogs
- Inhibition of Candida albicans biofilm formation by farnesol, a quorum-sensing molecule
- Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol
Application
Quorum sensing research / Biofilm research
References
PubMed Literature
Documents
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Safety Data Sheet (SDS)
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Specifications
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