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CAS RN: 70024-40-7 | Product Number: T2751

Terazosin Hydrochloride Dihydrate

Chemical Structure of Terazosin Hydrochloride Dihydrate
×
× Terazosin Hydrochloride Dihydrate

Purity: >98.0%(HPLC)(N)
Synonyms:
  • 4-Amino-6,7-dimethoxy-2-[4-(tetrahydro-2-furoyl)-1-piperazinyl]quinazoline Hydrochloride Dihydrate
Product Documents:
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General Information | Specifications & Properties | Safety & Regulations | Applications & Literature

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100MG
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Product Number T2751
Purity / Analysis Method >98.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__1__9H__2__5N__5O__4·HCl·2H__2O = 459.93 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN 70024-40-7
Related CAS RN 63590-64-7&63074-08-8
Reaxys Registry Number 6495493
PubChem Substance ID 125307764
MDL Number

MFCD00941408
Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Water 7.0 to 9.0 %
NMR confirm to structure
Properties (reference)
Melting Point 274 °C
GHS
Related Laws:
RTECS# TK8046000
Transport Information:
HS Number 2934999090
Application
Terazosin Hydrochloride: A Long Acting α1-Selective Adrenoceptor Antagonist

Terazosin hydrochloride, a quinazoline derivative, is a long acting α1-selective adrenoceptor antagonist with a similar pharmacodynamic profile to prazosin [P0938]. Terazosin is known to relax vascular and prostate smooth muscle through blockade of α1-adrenoceptors, and lowers blood pressure by decreasing peripheral vascular resistance. In in vitro experiments, terazosin has been shown to contractions in human prostatic tissue, and it is used in the treatment for prostatic hyperplasia (BPH). In addition, some studies indicate that α1-selective adrenoceptor antagonists show suppression of human prostate cancer cell growth. (The product is for research purpose only.)

References


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