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Published TCIMAIL newest issue No.198
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CAS RN: 136310-93-5 | Product Number: T3032
Tiotropium Bromide
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 50MG |
€80.00
|
2 | 26 |
| 200MG |
€215.00
|
Contact Us | 23 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | T3032 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__2BrNO__4S__2 = 472.41 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 136310-93-5 |
| Related CAS RN
|
186691-13-4 |
| Reaxys Registry Number | 11069044 |
| PubChem Substance ID | 253660050 |
| Merck Index (14) | 9454 |
| MDL Number | MFCD00867027 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 230 °C |
| Maximum Absorption Wavelength | 240 nm |
| Solubility (soluble in) | Methanol |
GHS
Related Laws:
Transport Information:
| HS Number | 2934999090 |
Application
Tiotropium Bromide: A Potent Muscarinic Antagonist for M1-, M2- and M3-Receptors in Lung
Tiotropium bromide is an anticholinergic agent that antagonizes muscarinic M1-, M2- and M3-receptors in lung, and is approximately 10-fold more potent than ipratropium bromide [I0907].
References
- Tiotropium bromide (Ba 679 BR), a novel long-acting muscarinic antagonist for the treatment of obstructive airways disease
- Tiotropium bromide(a review)
- Preclinical evaluation of long-acting muscarinic antagonists: comparison of tiotropium and investigational drugs
- Effect of tiotropium bromide on airway inflammation and remodelling in a mouse model of asthma
- Highly sensitive assay for tiotropium, a quaternary ammonium, in human plasma by high-performance liquid chromatography/tandem mass spectrometry
- A rapid, stability-indicating RP-HPLC method for the simultaneous determination of formoterol fumarate, tiotropium bromide, and ciclesonide in a pulmonary drug product
PubMed Literature
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