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Published TCIMAIL newest issue No.199
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CAS RN: 17817-31-1 | Product Number: T3473
4',6,7-Trihydroxyisoflavone
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Purity: >95.0%(T)(HPLC)
Synonyms:
- Demethyltexasin
- Desmethylglycitein
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 200MG |
€81.00
|
1 | 7 |
| 1G |
€287.00
|
1 | 22 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | T3473 |
Purity / Analysis Method 
|
>95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__0O__5 = 270.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 17817-31-1 |
| Reaxys Registry Number | 1291621 |
| PubChem Substance ID | 468592853 |
| MDL Number | MFCD00016953 |
Specifications
| Appearance | Light yellow to Brown to Dark green powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 95.0 % |
Properties (reference)
| Maximum Absorption Wavelength | 326 nm (MeOH) |
| Solubility (soluble in) | Dimethylformamide |
GHS
Related Laws:
Transport Information:
| HS Number | 2932990090 |
Application
4',6,7-Trihydroxyisoflavone: One of the Hydroxylated Metabolites of Daidzein with Pharmacological Activities
4',6,7-Trihydroxyisoflavone is one of the hydroxylated metabolites of daidzein [D2668] which is one of the major isoflavonoids found in soy food and plants.1) It has been reported that 6,7,4'-trihydroxyisoflavone has several pharmacological activities, including tyrosinase inhibitory,2) anti-cancer,3) anti-obesity4) and cognitive enhancement properties.5) (The product is for research purpose only.)
References
- 1) Oxidative in Vitro Metabolism of the Soy Phytoestrogens Daidzein and Genistein
- 2) Identifying 6,7,4'-trihydroxyisoflavone as a potent tyrosinase inhibitor
- 3) 6,7,4'-Trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2
- 4) A metabolite of daidzein, 6,7,4'-trihydroxyisoflavone, suppresses adipogenesis in 3T3-L1 preadipocytes via ATP-competitive inhibition of PI3K
- 5) 6,7,4’-Trihydroxyisoflavone, a major metabolite of daidzein, improves learning and memory via the cholinergic system and the p-CREB/BDNF signaling pathway in mice
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