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CAS RN: 36062-04-1 | Product Number: T3587
Tetrahydrocurcumin
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Purity: >95.0%(GC)(T)
Synonyms:
- 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione
- 1,7-Bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 5G |
€85.00
|
Contact Us | 1 | |
| 25G |
€175.00
|
1 | 13 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | T3587 |
Purity / Analysis Method 
|
>95.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__2__1H__2__4O__6 = 372.42 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| CAS RN | 36062-04-1 |
| Reaxys Registry Number | 3485469 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 95.0 % |
| Purity(Neutralization titration) | min. 95.0 % |
| Melting point | 98.0 to 102.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 100 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2914500080 |
Application
Tetrahydrocurcumin: An Antioxidative Major Metabolite of Curcumin
Tetrahydrocurcumin (THC) is a major metabolite of curcumin [C0434, C2302] that lacks the α, β-unsaturated carbonyl moiety and occurs naturally in turmeric.1) The interest in THC research has recently increased due to its superiority over curcumin in water solubility, chemical stability, bioavailability, and antioxidant activity. Many studies have indicated that THC exhibits higher antioxidant activity, but curcumin appears to bind to and modulate the activities of a wide variety of targets.2-4) Therefore, THC is expected to act as a chemo-preventative agent. (The product is for research purpose only.)
References
- 1) Biotransformation of curcumin through reduction and glucuronidation in mice
- 2) Curcumin differs from tetrahydrocurcumin for molecular targets, signaling pathways and cellular responses (a review)
- 3) Chemopreventative effects of tetrahydrocurcumin on human diseases (a review)
- 4) The cancer chemopreventive and therapeutic potential of tetrahydrocurcumin (a review)
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