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Published TCIMAIL newest issue No.198
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CAS RN: 20316-62-5 | Product Number: T4196
Potengriffioside A
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Purity: >95.0%(HPLC)(qNMR)
Synonyms:
- [(2R,3S,4S,5R,6S)-6-[[5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxy]-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]methyl (E)-3-(4-Hydroxyphenyl)acrylate
- 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2E)-3-(4-hydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 100MG |
€325.00
|
Contact Us | 19 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | T4196 |
Purity / Analysis Method 
|
>95.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__3__0H__2__6O__1__3 = 594.53 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| CAS RN | 20316-62-5 |
| Reaxys Registry Number | 3642768 |
| MDL Number | MFCD00017454 |
Specifications
| Appearance | White to Light orange to Pale yellow green powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| Specific rotation | -58.0 to -64.0 deg(C=1, methanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 260 °C |
GHS
Related Laws:
| RTECS# | UD3375250 |
Transport Information:
| HS Number | 2938909090 |
Application
Efflux pump research
Potengriffioside A, also called tiliroside, has been reported to act as an efflux pump inhibitor.1) The compound didn’t display antibacterial activity against Staphylococcus aureus strain SA-1199B but, in combination with antibiotics, reduced those minimum inhibitory concentrations (MICs) (i.e. norfloxacin (N0817);16-fold, ciprofloxacin (C2510, C2227); 16-fold, lomefloxacin (L0216); four-fold, ofloxacin (O0403); two-fold).
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Modulation of Drug Resistance in Staphylococcus aureus by a Kaempferol Glycoside from Herissantia tiubae (Malvaceae)
- Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside
- Antioxidant and cytotoxic activities of naturally occurring phenolic and related compounds: A comparative study
- Tiliroside as a CAXII inhibitor suppresses liver cancer development and modulates E2Fs/Caspase-3axis
- Hepatoprotective principles from the flowers of Tilia argentea (Linden): structure requirements of tiliroside and mechanisms of action
- Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese–diabetic mice
Application
Potengriffioside A (another name: Tiliroside): A Glycosidic Flavonoid with Diverse Biological Activities
Potengriffioside A (another name: tiliroside) is a glycosidic flavonoid found in several dietary plants, such as rose hip, strawberry and raspberry. It has been reported that potengriffioside A has diverse biological activities such as anti-inflammatory, antioxidant, anticarcinogenic, hepatoprotective and anti-diabetic activities. (The product is for research purpose only.)
References
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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