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CAS RN: 1392399-03-9 | Product Number: B4211

BIX 01294 Trihydrochloride Hydrate

Purity: >85.0%(N)
  • 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine Trihydrochloride Hydrate
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Product Number B4211
Purity / Analysis Method >85.0%(N)
Molecular Formula / Molecular Weight C__2__8H__3__8N__6O__2·3HCl·xH__2O = 600.03  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 1392399-03-9
Related CAS RN 935693-62-2
PubChem Substance ID 253661562
Appearance White to Almost white powder to crystal
Purity(with Total Nitrogen) min. 85.0 %(calcd.on anh.substance)
Water 2.0 to 7.0 %
Properties (reference)
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BIX-01294: A Selective Histone Methyltransferase (G9a HMTase) and G9a-Like Protein (GLP) Inhibitor

BIX-01294 is a selective inhibitor of the G9a histone methyltransferase (G9a HMTase) and G9a-like protein (GLP), and has no effect on other known HMTases. Additionally, it has been reported that BIX-01294 improves the reprogramming efficiency in neural precursor cells (NPCs) transduced with Oct3/4-Klf4 to a level comparable to transduction with all four Yamanaka factors (Oct3/4, Sox2, Klf4, and c-Myc), in generating iPS cells using Oct4 and Klf4.


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