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CAS RN: 49843-98-3 | Product Number: C2739

6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide


Purity: >98.0%(HPLC)
Synonyms:
  • EX-527
Documents:
25MG
₹21,500
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Product Number C2739
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__3H__1__3ClN__2O = 248.71  
Physical State (20 deg.C) Solid
Storage Temperature -20°C
Condition to Avoid Heat Sensitive
CAS RN 49843-98-3
Reaxys Registry Number 416178
PubChem Substance ID 253660936
MDL Number

MFCD03009471

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 10.80 to 11.80 %
Melting point 179.0 to 183.0 °C
Properties (reference)
Melting Point 181 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
H319 : Causes serious eye irritation.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
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Application
EX-527: A Potent and Selective SIRT1 inhibitor

SIRT1 is a member of the sirtuin deacetylase family of enzymes that removes acetyl groups from lysine residues in histones and other proteins. EX-527, an indole derivative, is a potent and selective SIRT1 inhibitor that does not inhibit class I and class II histone deacetylases (HDACs) or other sirtuin deacetylase family members.

References


PubMed Literature


Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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