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CAS RN: 209216-23-9 | Product Number: E0899

Entecavir Monohydrate

Purity: >98.0%(T)(HPLC)
  • 9-[(1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]guanine Monohydrate
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Product Number E0899
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__2H__1__5N__5O__3·H__2O = 295.30  
Physical State (20 deg.C) Solid
CAS RN 209216-23-9
Related CAS RN 142217-69-4
Reaxys Registry Number 14632881
PubChem Substance ID 253660820
Merck Index (14) 3595
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Specific rotation [a]20/D +34.0 to +38.0 deg(C=0.25, H2O)(calcd.on anh.substance)
Water 4.0 to 9.0 %
Properties (reference)
Melting Point 259 °C(dec.)
Specific Rotation 36° (C=0.25,H2O)
Solubility in water Practically insoluble
Degree of solubility in water 2.4 g/l  
Solubility (soluble in) Dimethylformamide
Solubility (slightly sol. in) Methanol
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
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Transport Information:
Cefdinir: A Third-Generation Cephalosporin More Active Against Gram-Positive Organisms

Entecavir (ETV or BMS-200475), a deoxyguanosine analog, is rapidly phosphorylated in vivo to the active intracellular 5'-triphosphate form that inhibits replication of hepatitis B virus (HBV) and shows reduced activity against other viruses, including HIV-1, influenza and herpes simplex viruses. Entecavir is a nucleoside reverse transcriptase inhibitor (NRTI). It inhibits reverse transcription in the viral replication process. (The product is for research purpose only.)


PubMed Literature

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