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CAS RN: 23007-85-4 | Product Number: M2690
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Hydrochloride
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Purity: >98.0%(HPLC)
Synonyms:
- MPTP Hydrochloride
Documents:
| Size | Unit Price | Hyderabad | Chennai | Japan* | Quantity |
|---|---|---|---|---|---|
| 25MG |
₹6,500
|
5 | 2 | ≥20 |
|
| 100MG |
₹19,300
|
6 | Contact Us | ≥20 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day & Chennai stocks will be dispatched in 3-6 working days.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*Change currency to place order in USD.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 6.20 to 7.00 % |
| Melting point | 249.0 to 254.0 °C |
Properties (reference)
| Melting Point | 250 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | UT8358950 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
Application
パーキンソン病 (PD) モデル動物作成用の神経毒，MPTP塩酸塩
MPTP hydrochloride can lead to severe damage to the nigrostriatal dopaminergic system similar to that observed in Parkinson’s disease (PD). Therefore, it has been used to PD animal models. (The product is for research purpose only.)
References
- 1)Mitochondrial complex I deficiency in Parkinson's disease
- 2)Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
- 3)Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
- 4)Experimental models of Parkinson's disease (a review)
- 5)Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease (a review)
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