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CAS RN: 67604-48-2 | Product Number: N0072
Naringenin
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Purity: >93.0%(T)(HPLC)
Synonyms:
- 4',5,7-Trihydroxyflavanone
Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
₹4,700.00
|
4 | ≥40 |
|
| 25G |
₹7,400.00
|
4 | ≥40 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | N0072 |
| Purity / Analysis Method | >93.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__2O__5 = 272.26 |
| Physical State (20 deg.C) | Solid |
| CAS RN | 67604-48-2 |
| Reaxys Registry Number | 280888 |
| PubChem Substance ID | 87573466 |
| SDBS (AIST Spectral DB) | 7408 |
| Merck Index (14) | 6424 |
| MDL Number | MFCD00006844 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 93.0 area% |
| Purity(Neutralization titration) | min. 93.0 % |
Properties (reference)
GHS
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Application
Quorum sensing research / Biofilm research / Type III secretion system (T3SS) research
References
- Inhibition of Quorum Sensing (QS) in Yersinia enterocolitica by an Orange Extract Rich in Glycosylated Flavanones
- The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1
- Suppression of bacterial cell–cell signalling, biofilm formation and type III secretion system by citrus flavonoids
Application
Naringenin: A Flavanone with Numerous Biological Properties such as Antioxidant and Anti-Inflammatory Activities
Naringenin, a major flavanone, is found in the Chinese herbal medicines, tomatoes, grapefruits, and many other citrus fruits, and an aglycone form of Naringin [N0073]. It has been demonstrated to possess numerous biological properties such as antioxidant and anti-inflammatory activities.1) Naringin and naringenin inhibit some drug-metabolizing cytochrome P450 (CYP) 3A4 activity in human liver microsomes, which may result in drug-drug interactions.1) In addition, naringenin is used as a starting compound for organic synthesis.2,3) (The product is for research purpose only.)
References
- 1) Effect of citrus flavonoids, Naringin and Naringenin, on metabolic syndrome and their mechanisms of action (a review)
- 2) An efficient synthesis of the potent phytoestrogens 8-prenylnaringenin and 6-(1,1-dimethylallyl)naringenin by europium(III)-catalyzed Claisen rearrangement
- 3) Total synthesis of (-)-episilvestrol and (-)-silvestrol
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