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CAS RN: 87333-19-5 | Product Number: R0219

Ramipril


Purity: >98.0%(T)(HPLC)
Synonyms:
  • (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic Acid
Documents:
1G
₹7,000.00
1   20  
5G
₹18,500.00
1   12  

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Product Number R0219
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__3H__3__2N__2O__5 = 416.52 
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
Packaging and Container 1G-Glass Bottle with Plastic Insert (View image)
CAS RN 87333-19-5
Reaxys Registry Number 4214464
PubChem Substance ID 468592790
Merck Index (14) 8103
MDL Number

MFCD00865775

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 106.0 to 110.0 °C
Specific rotation [a]20/D +35.0 to +41.0 deg(C=1, 0.1N HCl in EtOH)
Properties (reference)
Melting Point 109 °C
Specific Rotation 40° (C=1,0.1 NHCl in EtOH)
Solubility (soluble in) Methanol
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H360 : May damage fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# GY5879600
Transport Information:
Application
Ramipril: An Angiotensin-Converting Enzyme (ACE) Inhibitor

Ramipril (Hoe 498) is an angiotensin-converting enzyme (ACE) inhibitor. Ramipril is a prodrug which is rapidly hydrolyzed to the active metabolite ramiprilat by hepatic cleavage of the ester group. ACE, a peptidyl dipeptidase, circulates in the plasma and is located on the surface of endothelial cells. ACE is catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Thereby, ACE inhibitors reduce peripheral vascular resistance and blood pressure. For your reference, we also have a related synthetic intermediate [B5344] of ramipril. (The product is for research purpose only.)

References


Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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