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CAS RN: 38194-50-2 | Product Number: U0099

Sulindac


Purity: >98.0%(T)(HPLC)
Synonyms:
  • (Z)-5-Fluoro-2-methyl-1-[(p-methylsulfinyl)benzylidene]-1H-indene-3-acetic Acid
  • (Z)-2-[5-Fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl]acetic Acid
Documents:
10G
₹7,200
7   ≥20 
50G
₹19,600
2   3  

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*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.


Product Number U0099
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__0H__1__7FO__3S = 356.41  
Physical State (20 deg.C) Solid
CAS RN 38194-50-2
PubChem Substance ID 354334891
Merck Index (14) 8982
MDL Number

MFCD00599589

Specifications
Appearance Light yellow to Brown powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 182.0 to 186.0 °C
Properties (reference)
Melting Point 184 °C
Maximum Absorption Wavelength 327(0.05mol/L methanolic HCl) nm
Solubility in water Insoluble
Solubility (very slightly) Alcohol,Methanol
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
H361 : Suspected of damaging fertility or the unborn child.
H317 : May cause an allergic skin reaction.
H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P272 : Contaminated work clothing should not be allowed out of the workplace.
P270 : Do not eat, drink or smoke when using this product.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P284 : Wear respiratory protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# NK8226000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group III
Application
Sulindac: A Nonsteroidal Anti-Inflammatory Drug (NSAID) with Unique Metabolisms

U0099

Sulindac is a nonsteroidal anti-inflammatory drug that has anti-inflammatory, analgesic and antipyretic activities. The mechanism of action, like that of other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition. Sulindac is a unique prodrug. Slindac is reversibly metabolized to sulindac sulfide [S0906] which has anti-inflammatory and analgesic properties and is irreversibly metabolized to sulindac sulfone which has been suggested to possess antiproliferative effects against tumors. (The product is for research purpose only.)

References


PubMed Literature


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