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CAS RN: 1195-08-0 | Product Number: F1322
5-Formyluracil
Purity: >98.0%(T)(HPLC)
Synonyms:
- Uracil-5-carboxaldehyde
- 2,4-Dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
- 2,4-Dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbaldehyde
Documents:
Size | Unit Price | Belgium | Japan* | Quantity |
---|---|---|---|---|
200MG |
75,00 €
|
1 | 16 |
|
1G |
255,00 €
|
1 | 14 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Product Number | F1322 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__5H__4N__2O__3 = 140.10 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Air Sensitive |
CAS RN | 1195-08-0 |
Reaxys Registry Number | 125791 |
MDL Number | MFCD00192185 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Volumetric Analysis) | min. 98.0 % |
NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
RTECS# | UV7700120 |
Transport Information:
HS Number | 2933599590 |
Application
5-Formyluracil: A Major Oxidation Product of Thymine in DNA, and an Epigenetic Modification of Cytosine and Thymine
5-Formyluracil is a major oxidation product of thymine in DNA, and an epigenetic modification of cytosine and thymine. Recently, it has been reported that the level of 5-formyluracil is higher in certain cancer tissues than in normal tissues adjacent to the tumor. Therefore, the detection of 5-formyluracil as a biomarker has attracted widespread attention.
References
- Cellular effects of 5-formyluracil in DNA (a review)
- Chemoselective labeling and site-specific mapping of 5-formylcytosine as a cellular nucleic acid modification (a review)
- Detection and Application of 5-Formylcytosine and 5-Formyluracil in DNA (a review)
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