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CAS RN: 63208-82-2 | Product Number: P2751

Pifithrin-α


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone Hydrobromide
Documents:
10MG
€110.00
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50MG
€387.00
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Product Number P2751
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__6H__1__8N__2OS·HBr = 367.31  
Physical State (20 deg.C) Solid
Storage Temperature -20°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Moisture Sensitive,Heat Sensitive
CAS RN 63208-82-2
Reaxys Registry Number 4943838
Merck Index (14) 7421
MDL Number

MFCD00417851

Specifications
Appearance White to Orange to Green powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Argentmetric Titration) min. 98.0 %
Properties (reference)
Melting Point 192 °C
GHS
Related Laws:
RTECS# KM5784250
Transport Information:
HS Number 2934208090
Application
Pifithrin-α (PFT-α): A p53 Inhibitor

p53 (Also known as Trp53 in mice, TP53 in humans) is a tumor suppressor protein that is frequently inactivated in tumors.1) Pifithrin-α (PFT-α) is a p53 inhibitor that blocks p53-dependent transcriptional activation and apoptosis.2-4) Other p53 Inhibitors: Cyclic Pifithrin-α Hydrobromide [C2826] and Pifithrin-μ [P2048].

References


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