Published TCIMAIL newest issue No.196
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 20235-78-3 | Product Number: T4108
2-Thiouridine
Purity: >98.0%(HPLC)(qNMR)
Synonyms:
- 1-β-D-Ribofuranosyl-2-thiouracil
- 1-β-D-Ribofuranosyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
- 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
Product Documents:
Size | Unit Price | Belgium | Japan* | Quantity |
---|---|---|---|---|
100MG |
150,00 €
|
1 | 36 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Product Number | T4108 |
Purity / Analysis Method | >98.0%(HPLC)(qNMR) |
Molecular Formula / Molecular Weight | C__9H__1__2N__2O__5S = 260.26 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Air Sensitive,Heat Sensitive |
CAS RN | 20235-78-3 |
Reaxys Registry Number | 28752 |
MDL Number | MFCD03788697 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(qNMR) | min. 98.0 % |
NMR | confirm to structure |
Properties (reference)
Melting Point | 215 °C |
GHS
Related Laws:
Transport Information:
HS Number | 2934999090 |
Application
2-Thiouridine: A Sulfur-Containing Thioribonucleoside Found in tRNA
2-Thiouridine (s2U) is a sulfur-containing thioribonucleoside found in tRNA. Thioribonucleosides have been reported to perform essential functions for accurate and efficient translation, including proper codon recognition in mRNA or stabilization of tRNA structure. In addition, 2-thiouridine is stabilizes U:A pairs and destabilizes U:G wobble pairs. Thus, thioribonucleosides, including 2-thiouridine, are used to study nucleic acid structure and function.
References
- Synthesis and studies on the effect of 2-thiouridine and 4-thiouridine on sugar conformation and RNA duplex
- Biosynthesis and functions of sulfur modifications in tRNA (a review)
- Transfer RNA modification: presence, synthesis, and function (a review)
- Replacing Uridine with 2-Thiouridine Enhances the Rate and Fidelity of Nonenzymatic RNA Primer Extension
- Thermodynamic insights into 2-thiouridine-enhanced RNA hybridization
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.