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CAS RN: 520-36-5 | Product Number: A1514
Apigenin
Purity: >98.0%(HPLC)
Synonyms:
- 4',5,7-Trihydroxyflavone
Documents:
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* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Product Number | A1514 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__1__5H__1__0O__5 = 270.24 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 520-36-5 |
Reaxys Registry Number | 262620 |
PubChem Substance ID | 87562965 |
Merck Index (14) | 730 |
MDL Number | MFCD00006831 |
Specifications
Appearance | Light yellow to Brown powder to crystal |
Purity(HPLC) | min. 98.0 area% |
NMR | confirm to structure |
Properties (reference)
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
RTECS# | LK9276000 |
Transport Information:
Application
Quorum sensing research / Biofilm research / Type III secretion system (T3SS) research
References
- The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1
Application
Apigenin: A Bioactive Flavonoid with Anti-Inflammatory, Anti-Oxidant and Anti-Cancer Properties
Apigenin is abundantly present in common fruits and vegetables. It has been recognized as a bioactive flavonoid shown to possess remarkable anti-inflammatory, anti-oxidant and anti-cancer properties, and used as a traditional medicine. Apigenin has been reported to have a broad range of biological activities. On the anti-inflammatory and anti-oxidant activities, it show suppression of lipopolysaccharide-induced cyclooxygenase-2 (COX-2) and nitric oxide synthase-2 activity. On the anti-cancer activities, it is a low toxicity and non-mutagenic protein kinase inhibitor. It inhibits the growth of thyroid cancer cells by attenuating epidermal growth factor receptor (EGF-R) tyrosine phosphorylation and phosphorylation of ERK mitogen-activated protein kinase (MAPK). (The product is for research purpose only.)
References
- Apigenin and cancer chemoprevention: progress, potential and promise (review)
- Apigenin: A Promising Molecule for Cancer Prevention (a review)
- Phenols, proanthocyanidins, flavones and flavonols in some plant materials and their antioxidant activities
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