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CAS RN: 341028-37-3 | Product Number: A3166

Alagebrium Chloride


Purity: >98.0%(HPLC)
Synonyms:
  • 4,5-Dimethyl-3-(2-oxo-2-phenylethyl)thiazolium Chloride
Documents:
200MG
¥7,800
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Product Number A3166
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__3H__1__4ClNOS = 267.77 
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic
CAS RN 341028-37-3
Related CAS RN 393121-34-1
Reaxys Registry Number 11745839
PubChem Substance ID 354335367
Merck Index (14) 203
MDL Number

MFCD09027398

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 96.0 %
Properties (reference)
Melting Point 212 °C(dec.)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
Transport Information:
Application
Alagebrium Chloride: An Advanced Glycation Endproduct (AGE) Crosslink Breaker

Alagebrium chloride (ALT-711) is an advanced glycation endproduct (AGE) crosslink breaker. AGE formation that occurs with aging and diabetes leads to the crosslinking of proteins formed by glycation reaction. The accumulations of AGEs contribute to the pathology events, such as age-related diseases. Alagebrium chloride was the first drug candidate to be clinically tested for the purpose of breaking the crosslinks caused by AGEs, but the development was discontinued. (The product is for research purpose only.)

References


PubMed Literature


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