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CAS RN: 57248-88-1 | Product Number: D3921

Disodium Pamidronate


Purity: >95.0%(T)
Synonyms:
  • Pamidronic Acid Disodium Salt
  • Disodium 3-Amino-1-hydroxypropane-1,1-diphosphonate
Documents:
100MG
¥10,400
2   17  

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1G
¥47,100

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Note:

Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.

Product Number D3921
Purity / Analysis Method >95.0%(T)
Molecular Formula / Molecular Weight C__3H__9NNa__2O__7P__2 = 279.03 
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
Packaging and Container 100MG-Glass Bottle with Plastic Insert (View image),  1G-Glass Bottle with Plastic Insert (View image)
CAS RN 57248-88-1
Related CAS RN 109552-15-0&40391-99-9
Reaxys Registry Number 6459607
PubChem Substance ID 87561576
Merck Index (14) 7003
MDL Number

MFCD11045314

Specifications
Appearance White to Almost white powder to crystal
Purity(Nonaqueous Titration) min. 95.0 %(calcd.on anh.substance)
Water max. 25.0 %
Properties (reference)
GHS
Pictogram Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
H371 : May cause damage to organs.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# SZ6525000
Transport Information:
Application
Reviews of pharmacology

References

  • Pamidronate: A Review of its Pharmacological Properties and Therapeutic Efficacy in Resorptive Bone Disease
    • A. Fitton, D. McTavish, Drugs 1991, 41, 289.
  • Structure-Activity Relationships for Inhibition of Farnesyl Diphosphate Synthase in Vitro and Inhibition of Bone Resorption in Vivo by Nitrogen-Containing Bisphosphonates
    • J. E. Dunford, K. Thompson, F. P. Coxon, S. P. Luckman, F. M. Hahn, C. D. Poulter, F. H. Ebetino, M. J. Rogers, J Pharmacol. Exp. Ther. 2001, 296, 235.


PubMed Literature


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