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CAS RN: 6559-91-7 | Product Number: D5653

4'-Demethylepipodophyllotoxin


Purity: >98.0%(HPLC)
Synonyms:
  • (5R,5aR,8aR,9S)-9-Hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one
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1G
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5G
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Product Number D5653
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__2__1H__2__0O__8 = 400.38  
Physical State (20 deg.C) Solid
Storage Temperature -20°C
Condition to Avoid Heat Sensitive
CAS RN 6559-91-7
Reaxys Registry Number 1358259
MDL Number

MFCD00189421

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Specific rotation [a]20/D -68.0 to -60.0 deg(C=0.65, MeOH)
Properties (reference)
Melting Point 255 °C
Specific Rotation -64° (C=0.65,MeOH)
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H360 : May damage fertility or the unborn child.
H350 : May cause cancer.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# LV2476200
Transport Information:
Application
4'-Demethylepipodophyllotoxin: A Key Synthetic Intermediate for the Preparation of Podophyllotoxin-Type Anti-Tumor Agents

4'-Demethylepipodophyllotoxin is a key synthetic intermediate for the preparation of podophyllotoxin[P1771]-type anti-tumor agents, including etoposide [E0675]. 4'-Demethylepipodophyllotoxin is also an antimitotic agent which binds to monomeric tubulin, preventing micro-tubule polymerization. (The product is for research purpose only.)

References


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