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CAS RN: 5983-09-5 | Product Number: D6106

2',3'-Dideoxyuridine


Purity: >97.0%(HPLC)(qNMR)
Synonyms:
  • ddU
  • d2U
  • 1-[(2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione
Documents:
250MG
¥39,800
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Product Number D6106
Purity / Analysis Method >97.0%(HPLC)(qNMR)
Molecular Formula / Molecular Weight C__9H__1__2N__2O__4 = 212.21 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 5983-09-5
Reaxys Registry Number 750592
MDL Number

MFCD00013359

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 97.0 area%
Purity(qNMR) min. 97.0 %
Melting point 124.0 to 128.0 °C
Specific rotation +31.0 to +35.0 deg(C=1, water)
NMR confirm to structure
Properties (reference)
Melting Point 126 °C
GHS
Related Laws:
Transport Information:
Application
2',3'-Dideoxyuridine: An Inactive 2',3'-Didehydro-2',3'-Dideoxyribonucleoside against HIV

2',3'-Dideoxyuridine (ddUrd) is a 2',3'-didehydro-2',3'-dideoxyribonucleoside (ddeN). Unlike other ddeNs, ddUrd has poor anti-HIV activity.1) This is in consistent with the failure of ddUrd to be efficiently anabolized intracellularly to its 5'-triphosphate metabolite. In fact, it has been reported that 2',3'-dideoxyuridine-5'-triphosphate (ddUTP) is a potent and selective inhibitor of HIV reverse transcriptase in the cell free system.2,3) (The product is for research purpose only.)

References


Documents (Note: Some products will not have analytical charts available.)
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