Maximum quantity allowed is 999
Please select the quantity
CAS RN: 12542-36-8 | Product Number: G0543
Gossypol Acetic Acid
Purity: >98.0%(T)(HPLC)
Synonyms:
- 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2'-binaphthalene]-8,8'-dicarbaldehyde Acetic Acid
- 2,2'-Bis(8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) Acetic Acid
Documents:
Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
---|---|---|---|---|
250MG |
¥18,300
|
1 | Contact Us | Contact Us |
1G |
¥60,000
|
4 | 3 | Contact Us |
Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock in other WH: 2-3 Business Days
* Please contact us if you need further information.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* Please contact us if you need further information.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Product Number | G0543 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__3__0H__3__0O__8·C__2H__4O__2 = 578.61 |
Physical State (20 deg.C) | Solid |
Storage Temperature | 0-10°C |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Hygroscopic,Heat Sensitive |
CAS RN | 12542-36-8 |
Merck Index (14) | 4528 |
MDL Number | MFCD00058385 |
Specifications
Appearance | White to Green to Brown powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Properties (reference)
Melting Point | 168 °C(dec.) |
GHS
Pictogram |
![]() |
Signal Word | Warning |
Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
RTECS# | MD7360000 |
Transport Information:
Application
Gossypol Acetic Acid: A Polyphenolic Compound with Anti-Tumor, Anti-Viral, and Anti-Spermatogenic Properties
Gossypol acetic acid (gossypol) is a polyphenolic compound found in the cotton plant (genus Gossypium).1-4) Gossypol is of medical interest because of its anti-tumor,1,4) anti-viral,2) and anti-spermatogenic3) properties. Because of the restricted rotation of the two naphthyl moieties, which are connected via a C-C bond, gossypol exists as (+) and (-) enantiomers, in spite of the absence of an asymmetric carbon.2) Biological studies shows that the (-) enantiomer of gossypol was more active than the (+) form.1,2) The (-) enantiomer, named AT-101, is expected to be a new antitumor agent.5,6) (The product is for research purpose only.)
References
- 1) Cytotoxicity of enantiomers of gossypol
- 2) Selective inhibition of human immunodeficiency virus type 1 replication by the (-) but not the (+) enantiomer of gossypol
- 3) In vitro effect of gossypol acetate on yellow perch (Perca flavescens) spermatozoa
- 4) Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells
- 5) AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance
- 6) Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101).
Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number is entered
Analytical Charts
Please enter Lot Number
Incorrect Lot Number is entered
The requested analytical chart is not available. Sorry for the inconvenience.