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CAS RN: 12542-36-8 | Product Number: G0543

Gossypol Acetic Acid


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2'-binaphthalene]-8,8'-dicarbaldehyde Acetic Acid
  • 2,2'-Bis(8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) Acetic Acid
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Product Number G0543
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__3__0H__3__0O__8·C__2H__4O__2 = 578.61  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic,Heat Sensitive
CAS RN 12542-36-8
Merck Index (14) 4528
MDL Number

MFCD00058385

Specifications
Appearance White to Green to Brown powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Properties (reference)
Melting Point 168 °C(dec.)
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# MD7360000
Transport Information:
Application
Gossypol Acetic Acid: A Polyphenolic Compound with Anti-Tumor, Anti-Viral, and Anti-Spermatogenic Properties

Gossypol acetic acid (gossypol) is a polyphenolic compound found in the cotton plant (genus Gossypium).1-4) Gossypol is of medical interest because of its anti-tumor,1,4) anti-viral,2) and anti-spermatogenic3) properties. Because of the restricted rotation of the two naphthyl moieties, which are connected via a C-C bond, gossypol exists as (+) and (-) enantiomers, in spite of the absence of an asymmetric carbon.2) Biological studies shows that the (-) enantiomer of gossypol was more active than the (+) form.1,2) The (-) enantiomer, named AT-101, is expected to be a new antitumor agent.5,6) (The product is for research purpose only.)

References


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