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CAS RN: 191732-72-6 | Product Number: L0332

Lenalidomide


Purity: >98.0%(HPLC)
Synonyms:
  • 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
  • 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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250MG
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Product Number L0332
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__3H__1__3N__3O__3 = 259.27  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 191732-72-6
MDL Number

MFCD07772307

Specifications
Appearance White to Orange to Green powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 95.0 %
Properties (reference)
Melting Point 271 °C
Solubility in water Insoluble
Degree of solubility in water 0.3 g/l  
Solubility (very slightly) Acetone,Methanol,Tetrahydrofuran,Toluene
Solubility (insoluble in) Ethanol
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H360 : May damage fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# TW7342160
Transport Information:
Application
Lenalidomide: An Immunomodulatory Agent with Antiangiogenic and Antineoplastic Properties

Lenalidomide (CC-5013), a more potent thalidomide [T2524] analogue such as pomalidomide [P2074], is an immunomodulatory agent with antiangiogenic and antineoplastic properties. It is reported that lenalidomide inhibits proliferation and induces apoptosis of certain hematopoietic tumor cells including multiple myeloma, mantle cell lymphoma, and myelodysplastic syndromes in vitro. Immunomodulatory properties of lenalidomide include activation of T cells and natural killer (NK) cells, increased numbers of NKT cells, and inhibition of pro-inflammatory cytokines (e.g., TNF-α and IL-6) by monocytes. (The product is for research purpose only.)

References


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