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CAS RN: 24280-93-1 | Product Number: M2216
Mycophenolic Acid
Purity: >98.0%(T)(HPLC)
Chemical Substance Law (ENCS):
5-6736
Synonyms:
- (E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid
Documents:
Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
More Stock Info
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1G |
¥6,600
|
≥40 | 26 | ≥40 |
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* For the case that without specific estimated shipping data, e.g.: If displayed as "will be shipped after 8 working days", the products will be shipped 8 working days later after ordering.
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock in other WH: 2-3 Business Days
* Please contact us if you need further information.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Product Number | M2216 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__7H__2__0O__6 = 320.34 |
Physical State (20 deg.C) | Solid |
Storage Temperature | 0-10°C |
Condition to Avoid | Heat Sensitive |
CAS RN | 24280-93-1 |
Reaxys Registry Number | 318158 |
PubChem Substance ID | 135726996 |
Merck Index (14) | 6327 |
MDL Number | MFCD00036814 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Melting point | 141.0 to 145.0 °C |
Properties (reference)
Melting Point | 143 °C |
GHS
Pictogram |
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Signal Word | Warning |
Hazard Statements | H302 : Harmful if swallowed. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
Chemical Substance Law (ENCS) |
5-6736 |
RTECS# | MP8050000 |
Transport Information:
Application
Mycophenolic acid (MPA): An Inhibitor of Inosine Monophosphate Dehydrogenase (IMPDH), Needed for the Growth of T Cells and B Cells
Mycophenolic acid (MPA) is an active metabolite of mycophenolate mofetil (MMF) [M2387] with immunosuppressant activity. MPA is a noncompetitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH), an important enzyme in the de novo synthesis of guanosine nucleotides in T and B lymphocytes. (The product is for research purpose only.)
References
- Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotdie depletion
- Characterization of human type I and type II IMP dehydrogenases
- Mycophenolic acid binding to human serum albumin: characterization and relation to pharmacodynamics
- Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid
- Mycophenolic Acid: A One Hundred Year Odyssey from Antibiotic to Immunosuppressant (a review)
- Validation of a rapid and sensitive liquid chromatography-tandem mass spectrometry method for free and total mycophenolic acid
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