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CAS RN: 50-35-1 | Product Number: T2524

(±)-Thalidomide


Purity: >98.0%(HPLC)(N)
Synonyms:
  • N-(2,6-Dioxo-3-piperidinyl)phthalimide
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Product Number T2524
Purity / Analysis Method >98.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__1__3H__1__0N__2O__4 = 258.23  
Physical State (20 deg.C) Solid
CAS RN 50-35-1
Reaxys Registry Number 30233
PubChem Substance ID 253662357
Merck Index (14) 9255
MDL Number

MFCD00153873

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Properties (reference)
Melting Point 276 °C
Maximum Absorption Wavelength 300 nm
Solubility in water Insoluble
Degree of solubility in water 60 mg/l   25 °C
Solubility (very soluble in) Dimethylformamide,Dioxane
Solubility (very slightly) Ethanol,Acetone,Methanol
Solubility (insoluble in) Benzene,Ether,Chloroform
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
H312 : Harmful in contact with skin.
H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell.
P405 : Store locked up.
Related Laws:
RTECS# TI4375000
Transport Information:
UN Number UN2811
Class 6.1
Packing Group III
Application
Thalidomide: An Inhibitor of Angiogenesis

Thalidomide was originally used to treat morning sickness, but was banned as a human teratogen in the 1960s. In the 1990s, thalidomide has been discovered to have anti-inflammatory and anti-angiogenic properties, and is identified as an effective treatment for multiple myeloma. A recently approved amino analogue of thalidomide is pomalidomide [P2074]. (The product is for research purpose only.)

References


PubMed Literature


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