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CAS RN: 129830-38-2 | Product Number: Y0018

Y 27632 Dihydrochloride


Purity: >98.0%(HPLC)
Synonyms:
  • (1R,4r)-4-[(R)-1-Aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide Dihydrochloride
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Product Number Y0018
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__4H__2__1N__3O·2HCl = 320.26  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Hygroscopic,Heat Sensitive
CAS RN 129830-38-2
Reaxys Registry Number 9163222
MDL Number

MFCD03490488

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Water max. 8.0 %
Properties (reference)
Melting Point 252 °C(dec.)
Specific Rotation +4.0° (C=1,MeOH)
GHS
Related Laws:
Transport Information:
Application
Y-27632: A Rho associated Coiled-Coil Forming Protein Serine/Threonine Kinase (ROCK) Inhibitor

Y-27632 is a cell-permeable and selective Rho associated coiled-coil forming protein serine/threonine kinase (ROCK) inhibitor. ROCK is a serine-threonine protein kinase that has been identified as a target protein for the small GTP-binding protein Rho. It has been reported that ROCK is involved in various physiological function, including smooth muscle contraction and changes in cell morphology. ROCK inhibitors are expected to be applied to stem cell research reagents as well as to agents for hypertension and glaucoma. (The product is for research purpose only.)

References


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